Pilot Grants Program Cycle 4A

The National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer’s Disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory is happy to announce a Request for Applications (RFA) for the Pilot Grants Program Cycle 4A.

In this cycle, the IMPACT Collaboratory will fund up to five 1-year awards for pilot pragmatic clinical trials (ePCTs) that test non-pharmacological interventions embedded in health care system(s) for people living with AD/ADRD and their care partners. Pilot Studies will be funded for up to $175,000 in direct costs for a maximum of 12-months. For more information, please see our Pilot Grants Program page.

The goal of the pilot projects is to generate the preliminary data necessary to design and conduct a future full-scale Stage IV effectiveness ePCT (based on the NIH Stage Model) funded through other grant mechanisms (NIH or other sources).

The IMPACT Collaboratory will consider all applications for pilot ePCTs that evaluate non-pharmacological interventions to improve the care of people living with AD/ADRD and their care partners. This grant cycle will prioritize applications for interventions in these populations that aim to:

• Improve care through behavioral economics “nudge” interventions;
• Reduce inequities in health care;
• Reduce potentially inappropriate medications through de-prescribing; or
• Improve care in emergency departments.

Informational Webinar
An optional informational webinar will be hosted to provide investigators with an overview of application details and an opportunity to ask questions. Pre-registration is required using the link below.

February 14, 2022 @ 2pm ET. Register here

Letters of Intent Due - Required
Interested applicants are required to submit an LOI. LOIs are accepted on a rolling basis.
March 4, 2022 @ 5pm ET