2026 NIA Demonstration Projects Program

The National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer’s Disease and Alzheimer’s Disease-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory is now accepting applications for the Demonstration Projects Program for non-pharmacological interventions for people living with dementia (PLWD) and their care partners.

The IMPACT Collaboratory will fund up to two Demonstration Projects, each providing up to $800,000 in total direct costs over a 24-month period. These awards support full-scale, Stage IV effectiveness embedded Pragmatic Clinical Trials (ePCTs) (based on the NIH Stage Model). Projects must evaluate the effectiveness of non-pharmacological interventions embedded within health care systems for PLWD and their care partners. The goal of the Demonstration Project is to generate evidence on effective care delivery practices that can be expanded and implemented in other systems.

Read the full RFA here. 

For more information, join the informational webinar on September 16th (see details below) and visit our Demonstration Projects Program webpage. Learn more about our previous Demonstration Project Grant Awardees