- Today, @AmerGeriatrics released a new clinical framework to guide safe and patient-centered prescribing of obesity medications in older adults in @AGSJournal. Read more at: https://doi.org/10.1111/jgs.70769
New York, NY (October 29, 2026) – Today, the American Geriatrics Society (AGS) released a new framework to assist clinicians to safely prescribe obesity medications in older adults.
Organized around a series of cases, the framework offers a practical approach to prescribing obesity medications, including GLP-1 medications, that act through gut-derived hormonal pathways to older adults. While these medications offer promising benefits for weight management, glycemic control, and other health conditions, older adults are under-represented in clinical trials. The AGS framework emphasizes that clinicians should carefully consider age-related factors such as sarcopenia and frailty, risk of lean muscle loss, malnutrition, and dehydration.
This new paper, developed by the AGS Healthy Aging Special Interest Group, discusses key considerations for the use of obesity medications in older adults. The paper explores how to apply the Geriatrics 5Ms Framework (Mind, Mobility, Medications, Multicomplexity, and Matters Most) to incretin therapy in older adults.